The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityThe biological activity of recombinant swine IP10 was determined in a chemotaxis assay using a Boyden chamber. Swine PBMCs were activated with PHA for 3 days followed by treatment with IL-2. Bioactivity is typically detected at 10 ng/mL.
% SDS-PAGE. ab87388 is purified using Ion-exchange chromatography.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionReconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Interferon gamma induced factor MOB1, mouse, homolog of
Interferon gamma induced protein 10
10 kDa interferon gamma induced protein
10 kDa interferon gamma-induced protein
C X C motif chemokine 10
Chemokine (C X C motif) ligand 10
Chemokine CXC motif ligand 10
Interferon activated gene 10
Interferon gamma induced cell line
Interferon inducible cytokine IP 10
Interferon inducible cytokine IP10
Protein 10 from interferon (gamma) induced cell line
Small inducible cytokine B10
Small inducible cytokine B10 precursor
Small inducible cytokine subfamily B (Cys X Cys) member 10
Small inducible cytokine subfamily B CXC member 10
Small inducible cytokine subfamily B, member 10
Small-inducible cytokine B10
FunctionChemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
Post-translational modificationsCXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.