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Source Escherichia coli
Amino Acid Sequence
Sequence The sequence of the first five N-terminal amino acids was determined and was found to be Gly-Lys-Pro-Phe-Ile. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 95
% SDS-PAGE. This product is purified by proprietary chromatographic techniques.
Purity: Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Additional notes For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.0045mM Sodium Bicarbonate.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution Reconstitute in sterile 18MOhm/cm water to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Tissue specificity Expressed in breast, placenta, kidney, liver and pancreas.
Sequence similarities Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains.
Domain The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.
Cellular localization Secreted and Membrane.
Information by UniProt
References for Recombinant rabbit Prolactin Receptor protein (ab73248)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"