Recombinant rat Activin A protein (Animal Free) (ab187233)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Rat
    • Sequence
      MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
    • Molecular weight
      26 kDa
    • Amino acids
      309 to 424
    • Additional sequence information
      Mature non-glycosylated homodimer, containing two 117 amino acid chains.

Specifications

Our Abpromise guarantee covers the use of ab187233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL.

  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Endotoxin level
    <=1.000 Eu/µg
  • Purity
    >95% by SDS-PAGE .
    The purity of ab187233 is determined under reducing and non-reducing conditions.
  • Form
    Lyophilised
  • Additional notes

    This product is produced with no animal-derived raw products, animal free equipment and animal free protocols.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can then be further diluted to other aqueous solutions.

General Info

  • Alternative names
    • Activin A
    • Activin beta A chain
    • Activin beta-A chain
    • ActivinA
    • EDF
    • Erythroid differentiation factor
    • Erythroid differentiation protein
    • INHBA
    • INHBA_HUMAN
    • Inhibin beta A chain
    see all
  • Function
    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • Sequence similarities
    Belongs to the TGF-beta family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab187233 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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