The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
>95% by SDS-PAGE .
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at 4°C prior to reconstitution. Upon reconsitution add a carrier protein (0.1% BSA). Store at +4°C. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
pH: 7.40 Constituents: 95% PBS, 5% Trehalose
Lyophilized from 0.22 µm filtered solution.
It is recommended to reconstitute the lyophilized protein in sterile deionized water to a final concentration of 1mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.
beta chain of MHC class I molecules
c fragment of IgG, receptor, transporter, alpha
Fc Fragment of IgG, receptor transporter, alpha
FcRn alpha chain
IgG Fc fragment receptor transporter alpha chain
IgG receptor FcRn large subunit p51
immunoglobulin receptor, intestinal, heavy chain
major histocompatibility complex class I-like Fc receptor
Neonatal Fc receptor
neonatal Fc-receptor for Ig
FCGRT + B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk.
FCGRT has a possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
FCGRT: Cell membrane; Single-pass type I membrane protein
SDS-PAGE - Rat B2M + FCGRT protein fragment (ab191649)
SDS-PAGE analysis of DTT-reduced ab191649 stained overnight with Coomassie Blue. DTT-reduced protein migrates as 45-50 kDa (FCGRT) and 14.5 kDa (B2M) respectively due to different glycosylation.
has not yet been referenced specifically in any publications.
Publishing research using ab191649? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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