The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityDetermined by its ability to chemoattract purified blood eosinophils using a concentration range of 0.1-1.0 ug/ml.
% SDS-PAGE. ab125832 is purified by proprietary chromatographic techniques. Purity is greater than 97.0% as determined by RP-HPLC and SDS-PAGE.
Additional notesUpon reconstitution ab125832 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Determined by its ability to chemoattract purified blood eosinophils using a concentration range of 0.1-1.0 ug/ml.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.
pH: 7.40 Constituent: 99% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution It is recommended to reconstitute the lyophilized ab125832 in ultra pure sterile water to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
C-C motif chemokine 11
chemokine (C-C motif) ligand 11
Chemokine C C motif ligand 11
Chemokine CC Motif Ligand 11
Chemokine ligand 11
Eosinophil chemotactic protein
Small inducible cytokine A11
Small inducible cytokine subfamily A (Cys Cys) member 11
small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
Small inducible cytokine subfamily A member 11
Small-inducible cytokine A11
FunctionIn response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
Post-translational modificationsO-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.