Recombinant rat FNTA + FNTB protein (ab90793)

Overview

  • Product name
    Recombinant rat FNTA + FNTB protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Rat

Associated products

Specifications

Our Abpromise guarantee covers the use of ab90793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: 1 pmol of FTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 5mM DTT, 100mM Sodium chloride, 100mM HEPES, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CAAX farnesyltransferase subunit alpha
    • CAAX farnesyltransferase subunit beta
    • FNTA
    • FNTB
    • FTase alpha
    • FTase beta
    • FTase-alpha
    • FTase-beta
    • GGTase-I-alpha
    • Protein farnesyltransferase subunit beta
    • Protein farnesyltransferase/geranylgeranyltransferase type 1 subunit alpha
    • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
    • Ras proteins prenyltransferase subunit alpha
    • Ras proteins prenyltransferase subunit beta
    • Type I protein geranyl-geranyltransferase subunit alpha
    see all
  • Relevance
    FNT catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. FNTA (alpha subunit) is thought to participate in a stable complex with the substrate. FNTB (beta subunit) binds the peptide substrate.

References

ab90793 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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