This product is an active protein and may elicit a biological response in vivo, handle with caution.
CAAX farnesyltransferase alpha subunit
Farnesyltransferase alpha subunit
Farnesyltransferase CAAX box alpha
Geranylgeranyl transferase type I subunit beta
Geranylgeranyltransferase type I beta subunit
GGTase I alpha
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
Protein geranylgeranyltransferase type I, beta subunit
Ras proteins prenyltransferase alpha
Type I protein geranyl geranyltransferase alpha subunit
RelevanceGeranyl-Geranyl-Transferase catalyzes the transfer of the farnesyl and geranylgeranyl groups from farnesyl and geranylgeranyl-diphosphate to proteins containing a C-terminal CaaX motif, where ’C’ is a conserved cysteine that is the site of farnesyl modification, ’a’ is usually an aliphatic amino acid, and ’X’ is leucine or phenylalanine. Farnesyltransferase (FT) and GGTase-I are closely related, sharing a common a subunit and 30% identity in their ß subunits.
References for Recombinant rat Geranyl-Geranyl-Transferase protein (ab90114)
has not yet been referenced specifically in any publications.
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