Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Rat
    • Molecular weight
      15 kDa
    • Amino acids
      18 to 144

Specifications

Our Abpromise guarantee covers the use of ab123753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The ED50 determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is <0.01 ng/ml, corresponding to a specific activity of >1 x 108 units/mg.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity
    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by HPLC and SDS-PAGE. Endotoxin level is <0.1 ng per µg GM-CSF.
  • Form
    Lyophilised
  • Additional notes
    Endotoxin Level: <0.1 ng/µg.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    pH: 8.50
    Constituent: 0.12% Tris

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.

General Info

  • Alternative names
    • Colony stimulating factor
    • Colony Stimulating Factor 2
    • Colony stimulating factor 2 (granulocyte-macrophage)
    • Colony-stimulating factor
    • CSF
    • CSF 2
    • CSF2
    • CSF2_HUMAN
    • GM-CSF
    • GMCSF
    • Granulocyte Macrophage Colony Stimulating Factor
    • Granulocyte-macrophage colony-stimulating factor
    • MGC131935
    • MGC138897
    • MGI1GM
    • Molgramostin
    • Pluripoietin-a
    • Sargramostim
    see all
  • Function
    Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
  • Sequence similarities
    Belongs to the GM-CSF family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab123753 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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