Recombinant Rat GNAT3 co-expressed with Gß1?2 protein (ab90419)

Overview

  • Product name
    Recombinant Rat GNAT3 co-expressed with Gß1?2 protein
  • Protein length
    Full length protein
  • Description
    Recombinant Rat GNAT3 co-expressed with Gß1γ2 protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Rat

Specifications

Our Abpromise guarantee covers the use of ab90419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

General Info

  • Alternative names
    • G gamma-I
    • GNAT3
    • GNB1
    • GNG2
    • Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
    • Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
    • Guanine nucleotide-binding protein G(t) subunit alpha-3
    • Gustducin alpha-3 chain
    • Transducin beta chain 1
    see all
  • Relevance
    GNAT3 is a transducin-like heterotrimeric guanine nucleotide-binding protein (G-protein) expressed in taste receptor cells (TRCs) of the tongue. It is also expressed in the stomach and intestine in brush cells that are scattered throughout the surface epithelium of the gut and share structural features of taste receptor cells of the tongue. GNAT3 was demonstrated to be myristolated and was also palmitoylated in insect cells. Biochemical and genetic studies have implicated GNAT3 as a key component in the transduction of both bitter and sweet taste. GNAT3 mediates two responses, i.e. a decrease in cyclic nucleotide monophosphates via activation of phosphodiesterase 1A by GNAT3-alpha and activation of phospholipase C-beta by released G-beta-gamma subunits.

References

ab90419 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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