Recombinant rat GRO gamma protein (ab125819)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Rat
    • Sequence
      RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSDKSS
    • Molecular weight
      8 kDa
    • Amino acids
      33 to 101
    • Additional sequence information
      GRO-g Rat Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 69 amino acids and having a molecular mass of 7.8kDa.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125819 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml, corresponding to a specific activity of 10,000-100,000 units/mg.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity
    > 95 % SDS-PAGE.
    ab125819 is purified by proprietary chromatographic techniques. Purity is greater than 97.0% as determined by RP-HPLC and SDS-PAGE.
  • Form
    Lyophilised
  • Additional notes
    Upon reconstitution ab125819 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 7.40
    Constituent: 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    It is recommended to reconstitute the lyophilized ab125819 in sterile 18Mcm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

General Info

  • Alternative names
    • C-X-C motif chemokine 3
    • C-X-C motif chemokine ligand 3
    • Chemokine (C X C motif) ligand 3
    • Chemokine (CXC motif) ligand 3
    • Cinc 2
    • CINC 2b
    • Cinc2
    • CINC2b
    • CXCL 3
    • Cxcl3
    • CXCL3_HUMAN
    • Cytokine induced neutrophil chemoattractant 2
    • Dcip1
    • Dendritic cell inflammatory protein 1
    • Gm1960
    • GRO protein gamma
    • GRO-gamma
    • GRO-gamma(1-73)
    • GRO-gamma(5-73)
    • GRO3
    • GRO3 oncogene
    • GROG
    • Growth regulated protein gamma
    • Growth-regulated protein gamma
    • Macrophage inflammatory protein 2 beta precursor
    • Macrophage inflammatory protein 2-beta
    • Melanoma growth stimulatory activity gamma
    • Member 3
    • MGSA gamma
    • MIP 2b
    • MIP2-beta
    • MIP2B
    • SCYB3
    • Small inducible cytokine subfamily B
    see all
  • Function
    Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab125819 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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