Recombinant rat GsaL protein (ab90723)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesRat

Specifications

Our Abpromise guarantee covers the use of ab90723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

  • FormLiquid
  • Additional notes


    GsαL is the long splice variant of the alpha subunit of stimulatory heterotrimeric Gs-proteins. It differs from the short splice variant (GsαS) by 15-amino acid insert between the Ras-like domain and the alpha helical domain. GsαL activates adenylate cyclase (AC) and possesses a lower GDPaffinity than GsαS. These differences in GDP-affinity have important consequences for receptor/Gprotein coupling and AC activation.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Adenylate cyclase stimulating G alpha protein
    • GNAS
    • GNAS complex locus
    • GNAS1
    • GSP
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms short
    • XLalphas
    see all
  • RelevanceGuanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.

References for Recombinant rat GsaL protein (ab90723)

ab90723 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam.

The only unmodified version of the protein that we have in our catalogue is ab90723, so that might be the best of them to use. However be aware that although the datasheet says that the protein is full length, ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"