Suppression of tumorigenicity 13 (colon carcinoma)
Suppression of tumorigenicity 13 protein
Suppression of tumorigenicity protein 13
FunctionOne HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Sequence similaritiesBelongs to the FAM10 family. Contains 1 STI1 domain. Contains 3 TPR repeats.