Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesRat

Specifications

Our Abpromise guarantee covers the use of ab73839 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab73839 is purified by proprietary chromatographic techniques. Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • FormLyophilised
  • Additional notesLigand binding to LRPAP1 is Ca2+ dependent and e.g. lipid receptors can be released from LRPAP1 by a buffer containing 10mM EDTA (cf. Bajari et al. 2005, see ref. below). Furthermore, buffers containing phosphate should be avoided (it would form precipitates with Ca2+).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline, pH 7.5

  • ReconstitutionReconstitute in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution ab73839 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

General Info

  • Alternative names
    • 39 kDa receptor-associated protein
    • A2MRAP
    • A2RAP
    • Alpha 2 macroglobulin receptor associated protein
    • Alpha 2 MRAP
    • Alpha-2-macroglobulin receptor-associated protein
    • Alpha-2-MRAP
    • AMRP_HUMAN
    • HBP44
    • Lipoprotein receptor associated protein
    • Low density lipoprotein receptor related protein associated protein 1
    • Low density lipoprotein receptor-related protein-associated protein 1
    • Low density lipoprotein related protein associated protein 1
    • Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein
    • low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)
    • Lrpap1
    • MGC138272
    • MRAP
    • MYP23
    • RAP
    see all
  • FunctionInteracts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
  • Involvement in diseaseNote=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
  • Sequence similaritiesBelongs to the alpha-2-MRAP family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationEndoplasmic reticulum. Cytoplasm. Cell surface. Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.
  • Information by UniProt

References for Recombinant Rat LRPAP1 protein (ab73839)

ab73839 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab73839.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"