Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Rat

Specifications

Our Abpromise guarantee covers the use of ab73839 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    ab73839 is purified by proprietary chromatographic techniques. Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • Form
    Lyophilised
  • Additional notes
    Ligand binding to LRPAP1 is Ca2+ dependent and e.g. lipid receptors can be released from LRPAP1 by a buffer containing 10mM EDTA (cf. Bajari et al. 2005, see ref. below). Furthermore, buffers containing phosphate should be avoided (it would form precipitates with Ca2+).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline, pH 7.5

  • Reconstitution
    Reconstitute in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution ab73839 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

General Info

  • Alternative names
    • 39 kDa receptor-associated protein
    • A2MRAP
    • A2RAP
    • Alpha 2 macroglobulin receptor associated protein
    • Alpha 2 MRAP
    • Alpha-2-macroglobulin receptor-associated protein
    • Alpha-2-MRAP
    • AMRP_HUMAN
    • HBP44
    • Lipoprotein receptor associated protein
    • Low density lipoprotein receptor related protein associated protein 1
    • Low density lipoprotein receptor-related protein-associated protein 1
    • Low density lipoprotein related protein associated protein 1
    • Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein
    • low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)
    • Lrpap1
    • MGC138272
    • MRAP
    • MYP23
    • RAP
    see all
  • Function
    Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
  • Involvement in disease
    Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
  • Sequence similarities
    Belongs to the alpha-2-MRAP family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Endoplasmic reticulum. Cytoplasm. Cell surface. Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.
  • Information by UniProt

References

ab73839 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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