The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 10% Glycerol
70 kDa lamin
LA delta 50
Lamin A delta 50
renal carcinoma antigen NYREN32
Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin A and C. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acids internal deletion within the carboxyl-terminal domain of the protein. Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of LMNA gene.
Cell Membrane, Cytoplasmic, intermediate filament and Nuclear
SDS-PAGE - Progerin protein (Rat) (ab93917)
ab93917 by SDS-PAGE (8% polyacrylamide) and stained with Coomassie Blue.
Lane 1: MWM
Lane 2: 4µg ab93917
Lane 3: 3µg ab93917
Lane 4: 2µg ab93917
Lane 5: 1µg ab93917
has not yet been referenced specifically in any publications.
Publishing research using ab93917? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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