Recombinant rat RAB27A delta C26 protein (ab90110)

Overview

  • Product nameRecombinant rat RAB27A delta C26 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesRat

Specifications

Our Abpromise guarantee covers the use of ab90110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityActivity: 100 pmol of protein can bind > 80 pmol of GDP.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Tris HCl, 2mM Beta mercaptoethanol, 100mM Sodium chloride, 10mM Magnesium chloride, 0.01mM GDP, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • GS2
    • GTP-binding protein Ram
    • Rab-27
    • RAB-27A
    • RAB27
    • RAB27A, member RAS oncogene family
    • RAM
    • Ras-related protein Rab-27A
    • Ras-related protein Rab27A
    see all
  • RelevanceRab27 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The monomeric GTPase Rab27 subfamily regulates the exocytosis of these cell-specific store organelles. Rab27 acts through organelle-specific effector proteins, such as granuphilin in pancreatic beta cells and melanophilin in melanocytes. The Rab27 and effector complex then interacts with proteins that are essential for membrane transport and fusion.
  • Cellular localizationPlasma membrane

References for Recombinant rat RAB27A delta C26 protein (ab90110)

ab90110 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"