This product is an active protein and may elicit a biological response in vivo, handle with caution.
GTP-binding protein Ram
RAB27A, member RAS oncogene family
Ras-related protein Rab-27A
Ras-related protein Rab27A
RelevanceRab27 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The monomeric GTPase Rab27 subfamily regulates the exocytosis of these cell-specific store organelles. Rab27 acts through organelle-specific effector proteins, such as granuphilin in pancreatic beta cells and melanophilin in melanocytes. The Rab27 and effector complex then interacts with proteins that are essential for membrane transport and fusion.
Cellular localizationPlasma membrane
References for Recombinant rat RAB27A delta C26 protein (ab90110)
has not yet been referenced specifically in any publications.
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