Recombinant rat RAB27A delta C26 protein (ab90110)

Overview

  • Product name
    Recombinant rat RAB27A delta C26 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Rat

Specifications

Our Abpromise guarantee covers the use of ab90110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: 100 pmol of protein can bind > 80 pmol of GDP.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Tris HCl, 2mM Beta mercaptoethanol, 100mM Sodium chloride, 10mM Magnesium chloride, 0.01mM GDP, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • GS2
    • GTP-binding protein Ram
    • Rab-27
    • RAB-27A
    • RAB27
    • RAB27A, member RAS oncogene family
    • RAM
    • Ras-related protein Rab-27A
    • Ras-related protein Rab27A
    see all
  • Relevance
    Rab27 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The monomeric GTPase Rab27 subfamily regulates the exocytosis of these cell-specific store organelles. Rab27 acts through organelle-specific effector proteins, such as granuphilin in pancreatic beta cells and melanophilin in melanocytes. The Rab27 and effector complex then interacts with proteins that are essential for membrane transport and fusion.
  • Cellular localization
    Plasma membrane

References for Recombinant rat RAB27A delta C26 protein (ab90110)

ab90110 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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