Recombinant Rubella Virus E2 protein (ab43033)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • Additional sequence informationThe protein contains the Rubellavirus E2 regions.

Specifications

Our Abpromise guarantee covers the use of ab43033 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityImmunoreactive with sera of Rubella virus-infected individuals.
  • Applications

    ELISA

    Western blot

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 8M Urea, 0.1M Sodium chloride, 20mM Imidazol

General Info

  • Alternative names
    • E2
    • E2 envelope glycoprotein
    • E2 glycoprotein
    • Spike glycoprotein E2
  • RelevanceRubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. The the two envelope glycoproteins E2 and E1 are found as a heterodimeric spike complex embedded in the lipid envelope. E2 envelope glycoprotein is responsible for viral attachment to target host cell, by binding to the cell receptor. Its transport to the plasma membrane depends on interaction with E1 protein. Rubella or German measles is a mild disease in children and adults, but can cause devastating problems if it infects the fetus, especially if infection is in the first few weeks of pregnancy.

References for Recombinant Rubella Virus E2 protein (ab43033)

ab43033 has not yet been referenced specifically in any publications.

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