rna1 is the GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state. rna1 is located in the cytoplasm throughout the cell cycle and plays a direct role in protein import into the nucleus in S. cerevisiae and S. pombe. It contains 8 LRR (leucine-rich) repeats.
Cytoplasm. Cytoplasm; perinuclear region. Possibly enriched in the nuclear periphery.
References for Recombinant S. pombe rna1 protein (ab90201)
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