Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ15526
    • SequenceMGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ
    • Molecular weight24 kDa including tags
    • Amino acids80 to 273
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab117647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notesSurf1 protein although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 0.02% DTT, 20% Glycerol

General Info

  • Alternative names
    • OTTHUMP00000022473
    • OTTHUMP00000022474
    • SURF 1
    • SURF-1
    • Surf1
    • SURF1_HUMAN
    • Surfeit 1
    • Surfeit locus protein 1
    see all
  • FunctionProbably involved in the biogenesis of the COX complex.
  • Involvement in diseaseDefects in SURF1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.
  • Sequence similaritiesBelongs to the SURF1 family.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt

References for Recombinant Surf1 protein (ab117647)

ab117647 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"