The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Endotoxin level< 0.100 Eu/µg
Additional notesThe biological activity of this product is determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituent: 0.06% Acetic acid
This product is an active protein and may elicit a biological response in vivo, handle with caution.
C-C motif chemokine 25
Chemokine (C C motif) ligand 25
Chemokine (CC motif) ligand 25
Chemokine C C motif ligand 25
Chemokine CC motif ligand 25
Ck beta 15
Small inducible cytokine A25
Small inducible cytokine A25 isoform 1 precursor
Small inducible cytokine A25 isoform 2 precursor
Small inducible cytokine subfamily A (Cys Cys) member 25
Small inducible cytokine subfamily A Cys Cys member 25
Small inducible cytokine subfamily A, member 25
Small-inducible cytokine A25
Thymus expressed chemokine
FunctionPotentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
Tissue specificitySpecifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.