• Product nameAnti-REG4 antibody [MM0524-9B21]
    See all REG4 primary antibodies
  • Description
    Mouse monoclonal [MM0524-9B21] to REG4
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human REG4 protein.

  • Positive control
    • This antibody gave a positive result in IHC in the following FFPE tissue: Human colon Adenocarcinoma.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe IgG fraction of culture supernatant was purified by protein G affinity chromatography and 0.2 µm filtered.
  • ClonalityMonoclonal
  • Clone numberMM0524-9B21
  • IsotypeIgG2
  • Research areas


Our Abpromise guarantee covers the use of ab89917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/500 - 1/1000. Predicted molecular weight: 18 kDa.


  • FunctionMay be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
  • Tissue specificityHighly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Gastrointestinal secretory protein antibody
    • GISP antibody
    • Reg IV antibody
    • REG like protein antibody
    • REG-4 antibody
    • REG-like protein antibody
    • Reg4 antibody
    • REG4_HUMAN antibody
    • Regenerating gene type IV antibody
    • Regenerating islet derived family member 4 antibody
    • Regenerating islet derived protein 4 precursor antibody
    • Regenerating islet-derived protein 4 antibody
    • Regenerating islet-derived protein IV antibody
    • REGIV antibody
    • RELP antibody
    see all

Anti-REG4 antibody [MM0524-9B21] images

  • IHC image of REG4 staining in Human colon Adenocarcinoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab89917, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.


    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

References for Anti-REG4 antibody [MM0524-9B21] (ab89917)

ab89917 has not yet been referenced specifically in any publications.

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