Anti-Relaxin 3 receptor 1 antibody (ab72914)

Overview

  • Product nameAnti-Relaxin 3 receptor 1 antibody
    See all Relaxin 3 receptor 1 primary antibodies
  • Description
    Rabbit polyclonal to Relaxin 3 receptor 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human GPCR SALPR.

    (Peptide available as ab89370.)

  • Positive control
    • This antibody gave a positive signal in the SKNSH whole cell lysate and the following tissue lysates: Human brain; Human brain membrane; Human spinal cord; Human kidney.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab72914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

Target

  • FunctionReceptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
  • Tissue specificityExpressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor GPCR135 antibody
    • G protein coupled receptor SALPR antibody
    • G protein-coupled receptor SALPR antibody
    • G-protein coupled receptor GPCR135 antibody
    • GPCR 135 antibody
    • GPCR135 antibody
    • Gprotein coupled receptor SALPR antibody
    • Relaxin 3 receptor 1 antibody
    • Relaxin 3 receptor1 antibody
    • Relaxin 3/INSL7 receptor 1 antibody
    • Relaxin 3/INSL7 receptor1 antibody
    • Relaxin family peptide receptor 3 antibody
    • Relaxin family peptide receptor3 antibody
    • Relaxin-3 receptor 1 antibody
    • Relaxin/insulin like family peptide receptor 3 antibody
    • Relaxin3 receptor 1 antibody
    • Relaxin3 receptor1 antibody
    • RL3 R1 antibody
    • RL3R 1 antibody
    • RL3R1 antibody
    • RL3R1_HUMAN antibody
    • RLN3 receptor 1 antibody
    • RLN3 receptor1 antibody
    • RLN3R1 antibody
    • RXFP3 antibody
    • RXFPR3 antibody
    • SALP R antibody
    • SALPR antibody
    • somatostatin and angiotensin like peptide receptor antibody
    • Somatostatin- and angiotensin-like peptide receptor antibody
    see all

Anti-Relaxin 3 receptor 1 antibody images

  • All lanes : Anti-Relaxin 3 receptor 1 antibody (ab72914) at 1 µg/ml

    Lane 1 : Human brain tissue lysate - total protein (ab29466)
    Lane 2 : Human brain normal tissue lysate - membrane extract (ab29456)
    Lane 3 : Human spinal cord tissue lysate - total protein (ab29188)
    Lane 4 : SK N SH (Human neuroblastoma) Whole Cell Lysate
    Lane 5 : Human kidney tissue lysate - total protein (ab30203)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 51 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 15 kDa,37 kDa,49 kDa (possible glycosylated form). We are unsure as to the identity of these extra bands.

    Exposure time : 1 minute

References for Anti-Relaxin 3 receptor 1 antibody (ab72914)

ab72914 has not yet been referenced specifically in any publications.

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