Overview

  • Product nameAnti-Renin antibody
    See all Renin primary antibodies
  • Description
    Rabbit polyclonal to Renin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 70 - 302 of Human Renin (NP_000528).

  • Positive control
    • 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab97570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.

Target

  • FunctionRenin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
  • Involvement in diseaseDefects in REN are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
    Defects in REN are the cause of familial juvenile hyperuricemic nephropathy type 2 (HNFJ2) [MIM:613092]. It is a renal disease characterized by juvenile onset of hyperuricemia, slowly progressive renal failure and anemia.
  • Sequence similaritiesBelongs to the peptidase A1 family.
  • Cellular localizationSecreted. Membrane. Associated to membranes via binding to ATP6AP2.
  • Information by UniProt
  • Database links
  • Alternative names
    • Angiotensin forming enzyme antibody
    • Angiotensin forming enzyme precursor antibody
    • Angiotensinogenase antibody
    • Angiotensinogenase precursor antibody
    • FLJ10761 antibody
    • HNFJ2 antibody
    • REN antibody
    • Ren1 antibody
    • RENI_HUMAN antibody
    • Renin antibody
    • Renin precursor renal antibody
    see all

Anti-Renin antibody images

  • Anti-Renin antibody (ab97570) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 45 kDa

References for Anti-Renin antibody (ab97570)

ab97570 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab97570.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"