Anti-Repulsive Guidance Molecule B antibody (ab191916)

Overview

  • Product name
    Anti-Repulsive Guidance Molecule B antibody
    See all Repulsive Guidance Molecule B primary antibodies
  • Description
    Rabbit polyclonal to Repulsive Guidance Molecule B
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Repulsive Guidance Molecule B. The exact sequence is proprietary.
    Database link: Q6NW40

  • Positive control
    • HEK293T, NIH 3T3 and H9C2 whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.2
    Preservative: 0.05% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab191916 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 52 kDa (predicted molecular weight: 48 kDa).

Target

  • Function
    Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
  • Sequence similarities
    Belongs to the repulsive guidance molecule (RGM) family.
  • Post-translational
    modifications
    GPI-anchored.
  • Cellular localization
    Cell membrane. Membrane raft.
  • Information by UniProt
  • Database links
  • Alternative names
    • DRAGON antibody
    • DRG11-responsive axonal guidance and outgrowth of neurite antibody
    • Repulsive Guidance Molecule B antibody
    • RGM b antibody
    • RGM domain family member B antibody
    • Rgmb antibody
    • RGMB_HUMAN antibody
    see all

Images

  • All lanes : Anti-Repulsive Guidance Molecule B antibody (ab191916)

    Lane 1 : HEK293T whole cell lysate
    Lane 2 : NIH 3T3 whole cell lysate
    Lane 3 : H9C2 whole cell lysate

    Predicted band size: 48 kDa

References

ab191916 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191916.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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