Anti-Repulsive Guidance Molecule B antibody (ab96727)

Overview

  • Product name
    Anti-Repulsive Guidance Molecule B antibody
    See all Repulsive Guidance Molecule B primary antibodies
  • Description
    Rabbit polyclonal to Repulsive Guidance Molecule B
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment, corresponding to a region within the C terminal amino acids 219-467 of Human Repulsive Guidance Molecule B (NP_001012779)

  • Positive control
    • 293T, HeLaS3, HepG2, Molt-4, Raji cell lysates. A431, H1299 whole cell lysates. U87 xenograft.

Properties

Applications

Our Abpromise guarantee covers the use of ab96727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 52 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
  • Sequence similarities
    Belongs to the repulsive guidance molecule (RGM) family.
  • Post-translational
    modifications
    GPI-anchored.
  • Cellular localization
    Cell membrane. Membrane raft.
  • Information by UniProt
  • Database links
  • Alternative names
    • DRAGON antibody
    • DRG11-responsive axonal guidance and outgrowth of neurite antibody
    • Repulsive Guidance Molecule B antibody
    • RGM b antibody
    • RGM domain family member B antibody
    • Rgmb antibody
    • RGMB_HUMAN antibody
    see all

Images

  • All lanes : Anti-Repulsive Guidance Molecule B antibody (ab96727) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa S3 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 52 kDa
  • Immunohistochemical analysis of paraffin-embedded U87 xenograft, using ab96727 at 1/100 dilution.

References

ab96727 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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