Anti-Repulsive Guidance Molecule C antibody (ab86991)

Overview

  • Product nameAnti-Repulsive Guidance Molecule C antibody
    See all Repulsive Guidance Molecule C primary antibodies
  • Description
    Rabbit polyclonal to Repulsive Guidance Molecule C
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Human, Chimpanzee, Macaque Monkey, Gorilla, Chinese Hamster, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Mouse Repulsive Guidance Molecule C aa 100-200 conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q7TQ32

  • Positive control
    • This antibody gave a positive signal in the following lysates: Rat Embryonic Skeletal Muscle, Rat Post Natal Day Zero Skeletal Muscle and Rat Embryonic Heart.

Properties

Applications

Our Abpromise guarantee covers the use of ab86991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 49 kDa (predicted molecular weight: 45 kDa).

Target

  • RelevanceMutations in Repulsive Guidance Molecule (also known as RGM-C; HJV; hemojuvelin; Hfe2) cause juvenile hemochromatosis, a severe iron overload disease. RGM-C gene expression has been characterized in the developing mouse and found to be exclusively expressed in all striated muscle and in the myocardium.
  • Cellular localizationCell membrane; Lipid-anchor, GPI-anchor
  • Database links
  • Alternative names
    • 2310035L15Rik antibody
    • 5230400G09Rik antibody
    • AI414844 antibody
    • AI789733 antibody
    • DL M antibody
    • Haemojuvelin antibody
    • HEMOCHROMATOSIS antibody
    • HEMOCHROMATOSIS DUE TO DEFECT IN HEMOJUVELIN antibody
    • HEMOCHROMATOSIS DUE TO DEFECT IN HEPCIDIN ANTIMICROBIAL PEPTIDE antibody
    • HEMOCHROMATOSIS JUVENILE antibody
    • Hemochromatosis type 2 (juvenile) antibody
    • Hemochromatosis type 2 antibody
    • Hemochromatosis type 2 protein antibody
    • Hemochromatosis type 2 protein homolog antibody
    • HEMOCHROMATOSIS, TYPE 2A antibody
    • HEMOCHROMATOSIS, TYPE 2B antibody
    • Hemojuvelin antibody
    • HFE 2 antibody
    • Hfe2 antibody
    • HFE2A antibody
    • HJV antibody
    • JH antibody
    • Juvenile antibody
    • MGC23953 antibody
    • OTTHUMP00000059680 antibody
    • Repulsive guidance molecule c antibody
    • RGM C antibody
    • RGM domain family member C antibody
    • RGMC antibody
    see all

Anti-Repulsive Guidance Molecule C antibody images

  • All lanes : Anti-Repulsive Guidance Molecule C antibody (ab86991) at 1 µg/ml

    Lane 1 : Rat Embryonic Skeletal Muscle
    Lane 2 : Rat Post Natal Day Zero Skeletal Muscle
    Lane 3 : Rat Embryonic Day 18 Heart

    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 45 kDa
    Observed band size : 49 kDa (why is the actual band size different from the predicted?)

References for Anti-Repulsive Guidance Molecule C antibody (ab86991)

ab86991 has not yet been referenced specifically in any publications.

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