Overview

  • Product name
    Anti-RERE antibody [REREF1H8]
    See all RERE primary antibodies
  • Description
    Mouse monoclonal [REREF1H8] to RERE
  • Tested applications
    Suitable for: ICC/IF, Dot blot, WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment, corresponding to N terminal amino acids 50-200 of Human RERE

Properties

Applications

Our Abpromise guarantee covers the use of ab51374 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
Dot blot
WB
  • Application notes
    Dot: Use at an assay dependent dilution.
    ICC/IF: 1/100 (PMID 19131340).
    WB: Use at an assay dependent dilution. Predicted molecular weight: 172 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
    • Tissue specificity
      Widely expressed. Expressed in tumor cell lines.
    • Involvement in disease
      Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24).
    • Sequence similarities
      Contains 1 BAH domain.
      Contains 1 ELM2 domain.
      Contains 1 GATA-type zinc finger.
      Contains 1 SANT domain.
    • Domain
      The interaction with ATN1 is mediated by the coiled coil domain.
    • Cellular localization
      Nucleus. Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
    • Information by UniProt
    • Database links
    • Alternative names
      • 1110033A15Rik antibody
      • AI414665 antibody
      • ARG antibody
      • arginine glutamic acid dipeptide (RE) repeats antibody
      • arginine glutamic acid dipeptide repeats antibody
      • Arginine glutamic acid dipeptide repeats protein antibody
      • Arginine-glutamic acid dipeptide repeats protein antibody
      • ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE antibody
      • ARP antibody
      • ATN1L antibody
      • Atr2 antibody
      • atrophin 1 like antibody
      • Atrophin 1 like protein antibody
      • Atrophin 1 related protein antibody
      • atrophin 2 antibody
      • atrophin related protein antibody
      • ATROPHIN-1-ASSOCIATED PROTEIN antibody
      • Atrophin-1-like protein antibody
      • Atrophin-1-related protein antibody
      • atrophin-2 antibody
      • ATROPHIN-RELATED PROTEIN antibody
      • AW742570 antibody
      • DNB1 antibody
      • FLJ38775 antibody
      • KIAA0458 antibody
      • mKIAA0458 antibody
      • NEDBEH antibody
      • OTTHUMP00000001701 antibody
      • Rere antibody
      • RERE_HUMAN antibody
      see all

    Images

    • Lane 1 : Molecular weight markers
      Lane 2 : Anti-RERE antibody [REREF1H8] (ab51374)

      Lane 1 : As above
      Lane 2 : immunizing recombinant protein


      Predicted band size : 172 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    References

    This product has been referenced in:
    • Hou R & Sibinga NE Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells. J Biol Chem 284:6955-65 (2009). ICC/IF ; Rat . Read more (PubMed: 19131340) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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