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Irreversible vesicular monoamine transporter (VMAT2) antagonist
Irreversible vesicular monoamine transporter (VMAT2) antagonist. Long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Depletes biogenic amine stores. Antihypertensive and antipsychotic.
(3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
33H 40N 2O 9
Store at Room Temperature. The product can be stored for up to 12 months.
Soluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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References for Reserpine (ab120609)
This product has been referenced in:
et al. Reserpine causes biphasic nociceptive sensitivity alteration in conjunction with brain biogenic amine tones in rats. Neuroscience 169:1860-71 (2010).
Read more (PubMed: 20600634) »
et al. Inhibitory effect of reserpine on dopamine transporter function. Eur J Pharmacol 456:39-43 (2002).
Read more (PubMed: 12450567) »
et al. Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts. J Biol Chem 268:29-34 (1993).
Read more (PubMed: 8416935) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"