Anti-Respiratory Syncytial Virus antibody [8B10] (ab10016)


  • Product nameAnti-Respiratory Syncytial Virus antibody [8B10]
    See all Respiratory Syncytial Virus primary antibodies
  • Description
    Mouse monoclonal [8B10] to Respiratory Syncytial Virus
  • SpecificityNucleoprotein (N) protein specific. Reacts only with mature virions with completely assembled nucleocapsids. Fails to reorganize the N-protein epitope of immature and destroyed virions, which indicates conformation dependence of the 8B10 binding site. No cross-reactivity with influenza A and B viruses, adenovirus and parainfluenza type 1 and 2 viruses.
  • Tested applicationsSuitable for: ICC/IF, ELISAmore details
  • Immunogen

    Full length native protein (purified RSV virus, strain Long).

  • General notesConcentration varies from lot to lot and can be provided on request.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThis antibody has been affinity purified. Purity tested by elcetrophoresis.
  • ClonalityMonoclonal
  • Clone number8B10
  • MyelomaSp2/0
  • IsotypeIgG1
  • Research areas


Our Abpromise guarantee covers the use of ab10016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.


  • RelevanceRespiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
  • Cellular localizationVirion. Host cytoplasm
  • Alternative names
    • RS virus antibody
    • RSV antibody

Anti-Respiratory Syncytial Virus antibody [8B10] images

  • ab10016 staining Respiratory Syncytial Virus in apo E-deficient Mouse atherosclerotic plaque tissue by ICC/IF (Immunocytochemistry/immunofluorescence). Positive immunofluorescence for Respiratory Syncytial Virus is seen along the endothelial lining.

References for Anti-Respiratory Syncytial Virus antibody [8B10] (ab10016)

This product has been referenced in:
  • Haidari M  et al. Influenza virus directly infects, inflames, and resides in the arteries of atherosclerotic and normal mice. Atherosclerosis 208:90-6 (2010). Read more (PubMed: 19665123) »
  • Marchant D  et al. Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism. J Virol 84:11359-73 (2010). Read more (PubMed: 20702616) »

See all 2 Publications for this product

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Thank you for your inquiry. I have confirmed with the laboratory that we have tested this antibody with strain Long and unfortunately I do not have any information about reactivity with other strains. I hope this information is helpful. Please d...

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