Anti-Respiratory Syncytial Virus antibody (FITC) (ab20391)

Overview

  • Product name
    Anti-Respiratory Syncytial Virus antibody (FITC)
    See all Respiratory Syncytial Virus primary antibodies
  • Description
    Goat polyclonal to Respiratory Syncytial Virus (FITC)
  • Host species
    Goat
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Tested applications
    Suitable for: ICC/IF, ELISA, IHC-Pmore details
  • Species reactivity
    Does not react with Para 1-3, Influenza A & B or Adenovirus by IFA. Reacts well with bovine isolates. Negative against HEp-2 cells and WI-38 cells. Not yet tested in other species.
  • Immunogen

    Human RSV isolate

Properties

Applications

Our Abpromise guarantee covers the use of ab20391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 20647383
ELISA Use at an assay dependent concentration.
IHC-P 1/10 - 1/50.

Target

  • Relevance
    Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
  • Cellular localization
    Virion. Host cytoplasm
  • Alternative names
    • RS virus antibody
    • RSV antibody

Images

  • Immunofluorescence analysis of HRSV-infected A549 cells, staining Respiratory Syncytial Virus with ab20391. The cells were fixed with formalin and detected with primary antibody.

References

This product has been referenced in:
  • Aljabr W  et al. Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach. J Virol 90:4876-88 (2016). IF . Read more (PubMed: 26656699) »
  • Smith CM  et al. Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection. Am J Respir Crit Care Med 190:196-207 (2014). Read more (PubMed: 24941423) »

See all 4 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab20391.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up