Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133] (ab94966)
Key features and details
- Mouse monoclonal [RSV133] to Respiratory Syncytial Virus G Glycoprotein
- Suitable for: ELISA, WB, ICC/IF, IHC-Fr
- Reacts with: Respiratory syncytial virus
- Isotype: IgG1
Overview
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Product name
Anti-Respiratory Syncytial Virus G Glycoprotein antibody [RSV133] -
Description
Mouse monoclonal [RSV133] to Respiratory Syncytial Virus G Glycoprotein -
Host species
Mouse -
Tested applications
Suitable for: ELISA, WB, ICC/IF, IHC-Frmore details -
Species reactivity
Reacts with: Respiratory syncytial virus -
Immunogen
Tissue, cells or virus corresponding to Respiratory Syncytial Virus G Glycoprotein. Human RSV strain A2 infected HeLa cells
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General notes
Fusion partner: PS-NS/1-Ag4ab94966 is useful for the identification and location of expression of the G glycoprotein of Human Respiratory Syncytial Virus (HRSV) of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A purified -
Primary antibody notes
ab94966 is useful for the identification and location of expression of the G glycoprotein of Human Respiratory Syncytial Virus (HRSV) of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection. -
Clonality
Monoclonal -
Clone number
RSV133 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab94966 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
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ICC/IF |
Use at an assay dependent concentration.
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IHC-Fr |
Use at an assay dependent concentration.
Fix with Acetone. |
Notes |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 33 kDa. |
ICC/IF
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. Fix with Acetone. |
Target
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Relevance
Respiratory Syncytial Virus (RSV) G Glycoprotein attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. It interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, it lacks both neuraminidase and hemagglutinating activities. -
Cellular localization
Virion membrane. Host cell surface -
Alternative names
- Attachment glycoprotein G antibody
- G antibody
- Major surface glycoprotein G antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab94966 has been referenced in 6 publications.
- Chathuranga K et al. Inhibitory Effect of Sargassum fusiforme and Its Components on Replication of Respiratory Syncytial Virus In Vitro and In Vivo. Viruses 13:N/A (2021). PubMed: 33806073
- Chathuranga K et al. Anti-Respiratory Syncytial Virus Activity of Plantago asiatica and Clerodendrum trichotomum Extracts In Vitro and In Vivo. Viruses 11:N/A (2019). PubMed: 31277257
- Tiwari PM et al. Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection. Nat Commun 9:3999 (2018). PubMed: 30275522
- Vanover D et al. RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane. Nat Commun 8:667 (2017). PubMed: 28939853
- Shi H et al. Baicalin from Scutellaria baicalensis blocks respiratory syncytial virus (RSV) infection and reduces inflammatory cell infiltration and lung injury in mice. Sci Rep 6:35851 (2016). PubMed: 27767097
- Le Nouën C et al. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization. Proc Natl Acad Sci U S A 111:13169-74 (2014). PubMed: 25157129