Anti-Respiratory Syncytial Virus Subgroup A G Glycoprotein antibody [RSV1C2] (ab94967)

Overview

  • Product name
    Anti-Respiratory Syncytial Virus Subgroup A G Glycoprotein antibody [RSV1C2]
  • Description
    Mouse monoclonal [RSV1C2] to Respiratory Syncytial Virus Subgroup A G Glycoprotein
  • Tested applications
    Suitable for: ELISA, WB, ICC/IF, IHC-Frmore details
  • Species reactivity
    Reacts with: Other
  • Immunogen

    Human Respiratory Syncytial Virus strain A2 infected HeLa cells

  • General notes
    Myeloma: PS-NS/1-Ag4


    ab94967 is useful for the identification and location of subgroup A Respiratory Syncytial Virus G glycoprotein expression. This antibody confers passive protection against HRSV subgroup A in an animal model of Human Respiratory Syncytial Virus infection.
    Recommended growth conditions: Growth medium RPMI with 25mM Hepes, 2mM additional glutamine and 10% heat inactivated foetal calf serum

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Primary antibody notes
    ab94967 is useful for the identification and location of subgroup A Respiratory Syncytial Virus G glycoprotein expression. This antibody confers passive protection against HRSV subgroup A in an animal model of Human Respiratory Syncytial Virus infection.
    Recommended growth conditions: Growth medium RPMI with 25mM Hepes, 2mM additional glutamine and 10% heat inactivated foetal calf serum
  • Clonality
    Monoclonal
  • Clone number
    RSV1C2
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab94967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
ICC/IF Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration. Fix with Acetone.

Target

  • Relevance
    Respiratory Syncytial Virus (RSV) Subgroup A G Glycoprotein attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. It interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, it lacks both neuraminidase and hemagglutinating activities.
  • Cellular localization
    Virion membrane. Host cell surface
  • Alternative names
    • Attachment glycoprotein G antibody
    • G antibody
    • Major surface glycoprotein G antibody
    • Membrane bound glycoprotein antibody
    • mG antibody
    • RSV Subgroup A G Glycoprotein antibody
    see all

References

ab94967 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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