Overview

  • Product nameAnti-Reticulon 2 antibody
    See all Reticulon 2 primary antibodies
  • Description
    Rabbit polyclonal to Reticulon 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length Human Reticulon 2 protein (NP_996783.1).

  • Positive control
    • Mouse brain tissue lysate and Reticulon 2 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 59 kDa.

Target

  • Tissue specificityIsoform RTN2-C is highly expressed in skeletal muscle.
  • Involvement in diseaseSpastic paraplegia autosomal dominant 12 (SPG12) [MIM:604805]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Sequence similaritiesContains 1 reticulon domain.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Neuroendocrine specific protein like 1 antibody
    • Neuroendocrine-specific protein-like 1 antibody
    • Neuroendocrine-specific protein-like I antibody
    • NSP like protein 1 antibody
    • NSP-like protein 1 antibody
    • NSP-like protein I antibody
    • NSP2 antibody
    • NSPL1 antibody
    • NSPLI antibody
    • Reticulon-2 antibody
    • RTN2 antibody
    • RTN2_HUMAN antibody
    see all

Anti-Reticulon 2 antibody images

  • Anti-Reticulon 2 antibody (ab103170) at 1/500 dilution + Mouse brain tissue lysate at 50 µg

    Predicted band size : 59 kDa
  • All lanes : Anti-Reticulon 2 antibody (ab103170) at 1/500 dilution

    Lane 1 : RTN2 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 59 kDa

References for Anti-Reticulon 2 antibody (ab103170)

ab103170 has not yet been referenced specifically in any publications.

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