Anti-Retinal S antigen antibody [PDS1] (ab111108)

Overview

  • Product nameAnti-Retinal S antigen antibody [PDS1]
    See all Retinal S antigen primary antibodies
  • Description
    Mouse monoclonal [PDS1] to Retinal S antigen
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Sheep, Goat, Cow, Human, Pig
  • Immunogen

    Retinal S antigen isolated from Pig cells.

  • Positive control
    • Rat retina lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium azide
    Constituent: 99.5% Tissue culture supernatant
  • PurityTissue culture supernatant
  • ClonalityMonoclonal
  • Clone numberPDS1
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 45 kDa.
ELISA Use at an assay dependent concentration.
IHC-P 1/20.

Target

  • FunctionArrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
  • Tissue specificityRetina and pineal gland.
  • Involvement in diseaseDefects in SAG are a cause of congenital stationary night blindness Oguchi type 1 (CSNBO1) [MIM:258100]; also known as Oguchi disease. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNBO is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.
  • Sequence similaritiesBelongs to the arrestin family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 48 kDa protein antibody
    • Arrestin 1 antibody
    • Arrestin antibody
    • ARRS_HUMAN antibody
    • Retinal S antigen (48 KDa protein) antibody
    • Retinal S-antigen antibody
    • Rod photoreceptor arrestin antibody
    • RP47 antibody
    • S antigen antibody
    • S antigen retina and pineal gland (arrestin) antibody
    • S arrestin antibody
    • S-AG antibody
    • S-arrestin antibody
    • SAG antibody
    see all

Anti-Retinal S antigen antibody [PDS1] images

  • Immunohistochemistry was performed on Human retina tissue. To expose target protein antigen was retreived using 10mM sodium citrate followed by microwave treatment for 8-15 minutes. Endogenous peroxidases were blocked in 3% H202-methanol for 15 minutes and tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a Retinal S antigen mouse monoclonal antibody (ab111108) at a dilution of 1:20 overnight in a humidified chamber. Tissues were washed in PBST and detection was performed using a secondary antibody conjugated to HRP. DAB staining buffer was applied and tissues were counterstained with hematoxylin and prepped for mounting. Images were taken at 40X magnification.
  • Anti-Retinal S antigen antibody [PDS1] (ab111108) at 1/1000 dilution + Rat retina lysate

    Predicted band size : 45 kDa

References for Anti-Retinal S antigen antibody [PDS1] (ab111108)

ab111108 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"