Retinal S antigen peptide (ab4974)

Overview

  • Product nameRetinal S antigen peptide

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab4974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat S-arrestin, catalog ab3435. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names
    • 48 kDa protein
    • Arrestin
    • Arrestin 1
    • ARRS_HUMAN
    • Retinal S antigen (48 KDa protein)
    • Retinal S-antigen
    • Rod photoreceptor arrestin
    • RP47
    • S antigen
    • S antigen retina and pineal gland (arrestin)
    • S arrestin
    • S-AG
    • S-arrestin
    • SAG
    see all
  • FunctionArrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
  • Tissue specificityRetina and pineal gland.
  • Involvement in diseaseDefects in SAG are a cause of congenital stationary night blindness Oguchi type 1 (CSNBO1) [MIM:258100]; also known as Oguchi disease. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNBO is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.
  • Sequence similaritiesBelongs to the arrestin family.
  • Information by UniProt

References for Retinal S antigen peptide (ab4974)

ab4974 has not yet been referenced specifically in any publications.

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Thank you for contacting us and for your interest in our products.

I am sorry to confirm that as far as we are aware, ab4974 Retinal S antigen peptidehas never been tested in this type of application.This has beentested as a blocking peptide...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"