Anti-Retinoic Acid Receptor beta antibody (ab76778)


  • Product nameAnti-Retinoic Acid Receptor beta antibody
    See all Retinoic Acid Receptor beta primary antibodies
  • Description
    Mouse polyclonal to Retinoic Acid Receptor beta
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-448 of Human Retinoic Acid Receptor beta

  • Positive control
    • HeLa cells RARB transfected 293T cell lysate



Our Abpromise guarantee covers the use of ab76778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
ICC/IF Use a concentration of 10 µg/ml.


  • FunctionReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
  • Involvement in diseaseMicrophthalmia, syndromic, 12
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localizationCytoplasm and Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HAP antibody
    • HBV-activated protein antibody
    • NR1B2 antibody
    • Nuclear receptor subfamily 1 group B member 2 antibody
    • RAR B antibody
    • RAR beta antibody
    • RAR epsilon antibody
    • RAR-beta antibody
    • RAR-epsilon antibody
    • RARB antibody
    • RARB_HUMAN antibody
    • Retinoic acid receptor beta 2 antibody
    • Retinoic acid receptor beta 4 antibody
    • Retinoic acid receptor beta 5 antibody
    • Retinoic acid receptor beta antibody
    • Retinoic acid receptor beta polypeptide antibody
    • RRB2 antibody
    see all

Anti-Retinoic Acid Receptor beta antibody images

  • All lanes : Anti-Retinoic Acid Receptor beta antibody (ab76778) at 1/500 dilution

    Lane 1 : Retinoic Acid Receptor beta transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 50 kDa
    Observed band size : 50 kDa
  • HeLa cells labelled with ab76778 at 10 µg/ml followed by fluorescein conjugated secondary antibody.

References for Anti-Retinoic Acid Receptor beta antibody (ab76778)

ab76778 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Marmoset (common) Tissue sections (Adult testis)
Specification Adult testis
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Dako antigen retrieval solution
Permeabilization No
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 25°C

Zachary Yu-Ching Lin

Verified customer

Submitted Mar 26 2013