Anti-Retinoic Acid Receptor gamma 2 antibody (ab5905)

Overview

  • Product nameAnti-Retinoic Acid Receptor gamma 2 antibody
    See all Retinoic Acid Receptor gamma 2 primary antibodies
  • Description
    Rabbit polyclonal to Retinoic Acid Receptor gamma 2
  • SpecificityThis antibody does not detect RAR gamma-1, or either of the alpha or beta forms of RAR.
  • Tested applicationsSuitable for: IP, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human, Non Human Primates
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human Retinoic Acid Receptor gamma 2 aa 13-28 (N terminal).
    Sequence:

    RRLYGAAGPGAGLLRR


    (Peptide available as ab39774)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab5905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
WB 1/500 - 1/5000. Predicted molecular weight: 50 kDa.Can be blocked with Human Retinoic Acid Receptor gamma 2 peptide (ab39774).
EMSA Use 1µl for 102 cells.

Target

  • FunctionReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • NR1B3 antibody
    • Nuclear receptor subfamily 1 group B member 3 antibody
    • RAR gamma antibody
    • RAR gamma isoform 2 antibody
    • RAR gamma2 antibody
    • RAR-gamma antibody
    • RARC antibody
    • Rarg antibody
    • RARG_HUMAN antibody
    • retinoic acid nuclear receptor gamma variant 1 antibody
    • retinoic acid nuclear receptor gamma variant 2 antibody
    • Retinoic acid receptor gamma antibody
    see all

Anti-Retinoic Acid Receptor gamma 2 antibody images

  • All lanes : Anti-Retinoic Acid Receptor gamma 2 antibody (ab5905) at 1/1000 dilution

    Lane 1 : SK-BR-3 cell lysate
    Lane 2 : HeLa cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 50 kDa
    Observed band size : 50 kDa

References for Anti-Retinoic Acid Receptor gamma 2 antibody (ab5905)

ab5905 has not yet been referenced specifically in any publications.

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