Anti-Retinoic Acid Receptor gamma antibody (ab76776)

Overview

  • Product nameAnti-Retinoic Acid Receptor gamma antibody
    See all Retinoic Acid Receptor gamma primary antibodies
  • Description
    Mouse polyclonal to Retinoic Acid Receptor gamma
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-454 of Human Retinoic Acid Receptor gamma

  • Positive control
    • Retinoic Acid Receptor gamma transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab76776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

Target

  • FunctionReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • NR1B3 antibody
    • Nuclear receptor subfamily 1 group B member 3 antibody
    • RAR gamma antibody
    • RAR-gamma antibody
    • RARC antibody
    • Rarg antibody
    • RARG_HUMAN antibody
    • Retinoic acid receptor gamma 2 antibody
    • Retinoic acid receptor gamma antibody
    • Retinoic acid receptor, gamma antibody
    see all

Anti-Retinoic Acid Receptor gamma antibody images

  • All lanes : Anti-Retinoic Acid Receptor gamma antibody (ab76776) at 1/500 dilution

    Lane 1 : Retinoic Acid Receptor gamma transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
    Developed using the ECL technique

    Predicted band size : 50 kDa
    Observed band size : 50 kDa

References for Anti-Retinoic Acid Receptor gamma antibody (ab76776)

ab76776 has not yet been referenced specifically in any publications.

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