Anti-Retinoic Acid Receptor gamma antibody [H5620] (ab41938)

Overview

  • Product nameAnti-Retinoic Acid Receptor gamma antibody [H5620]
    See all Retinoic Acid Receptor gamma primary antibodies
  • Description
    Mouse monoclonal [H5620] to Retinoic Acid Receptor gamma
  • SpecificityThis antibody specifically recognizes RAR gamma but does not recognize RAR alpha and beta.
  • Tested applicationsSuitable for: ELISA, WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Baculovirus-expressed recombinant fragment: ATNKERLFAA GALGPGSGYP GAGFPFAFPG ALRGSPPFEM LSPSFRGLGQ PDLPKEMASL SVETQSTSSE EMVPSSPSPP PPPRVYK, corresponding to N terminal amino acids 2/88 of Human Retinoic Acid Receptor gamma

Properties

Applications

Our Abpromise guarantee covers the use of ab41938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IP
  • Application notesELISA: Use at a concentration of 0.06 µg/ml (A450 = 0.5).
    IP: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
    • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • NR1B3 antibody
      • Nuclear receptor subfamily 1 group B member 3 antibody
      • RAR gamma antibody
      • RAR-gamma antibody
      • RARC antibody
      • Rarg antibody
      • RARG_HUMAN antibody
      • Retinoic acid receptor gamma 2 antibody
      • Retinoic acid receptor gamma antibody
      • Retinoic acid receptor, gamma antibody
      see all

    References for Anti-Retinoic Acid Receptor gamma antibody [H5620] (ab41938)

    ab41938 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for taking time to contact us. I am sorry to hear that this antibody is not providing satisfactory results.

    From the WB image sent, it does look like you're getting a strong specific band at 50 kDa, which is the predicted MW for RA...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"