Anti-Retinoid X Receptor beta antibody (ab23939)

Overview

  • Product nameAnti-Retinoid X Receptor beta antibody
    See all Retinoid X Receptor beta primary antibodies
  • Description
    Goat polyclonal to Retinoid X Receptor beta
  • SpecificityDoes not cross react with either RXR alpha or gamma.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    (C)RDGMGDSGRDSRSP

    , corresponding to amino acids 70 - 83 of Human Retinoid X Receptor beta.

  • Positive control
    • Lysate prepared from A431 cells. Lysate prepared from transfected HEK293 cells transiently expressing Retinoid X Receptor beta.

Properties

Applications

Our Abpromise guarantee covers the use of ab23939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 59 kDa).

Target

  • RelevanceRetinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • DAUD I6 antibody
    • DAUDI6 antibody
    • H 2RIIBP antibody
    • H2RIIBP antibody
    • MGC1831 antibody
    • MHC class I promoter binding protein antibody
    • NR2B2 antibody
    • nuclear receptor subfamily 2 group B member 2 antibody
    • RCoR 1 antibody
    • RCoR1 antibody
    • Retinoic acid receptor RXR beta antibody
    • RXR beta antibody
    • RXRB antibody
    • RXRbeta antibody
    see all

Anti-Retinoid X Receptor beta antibody images

  • Anti-Retinoid X Receptor beta antibody (ab23939) at 1 µg/ml + A431 lysate (RIPA buffer) at 35 µg

    Predicted band size : 59 kDa
  • Anti-Retinoid X Receptor beta antibody (ab23939) at 3 µg/ml + lysate prepared from transfected HEK293 cells transiently expressing Retinoid X Receptor beta

    Predicted band size : 59 kDa
    Observed band size : 62 kDa (why is the actual band size different from the predicted?)

References for Anti-Retinoid X Receptor beta antibody (ab23939)

ab23939 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"