Anti-Retinoid X Receptor beta antibody - ChIP Grade (ab5793)

Overview

  • Product nameAnti-Retinoid X Receptor beta antibody - ChIP Grade
    See all Retinoid X Receptor beta primary antibodies
  • Description
    Rabbit polyclonal to Retinoid X Receptor beta - ChIP Grade
  • Tested applicationsSuitable for: ChIP, IHC - Wholemount, IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Cow, Human
    Predicted to work with: Rat, Dog
  • Immunogen

    Synthetic peptide corresponding to Mouse Retinoid X Receptor beta aa 190-202.
    Sequence:

    QKSDQGVEGPGAT

Properties

Applications

Our Abpromise guarantee covers the use of ab5793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ChIP Use at an assay dependent concentration.
IHC - Wholemount Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 63 kDa).

Detects a band of approximately 50 kDa representing RXR beta from COS cells transfected with the human gene (predicted molecular weight: 63 kDa).

EMSA Use at an assay dependent concentration.

Gel shift assays reveal supershifting of vitamin D receptor (VDR)/RXR beta/vitamin D receptor response element (VDRE) complexes when ab5739 is preincubated with RXR beta prior to addition of VDR.

Target

  • RelevanceRetinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • DAUD I6 antibody
    • DAUDI6 antibody
    • H 2RIIBP antibody
    • H2RIIBP antibody
    • MGC1831 antibody
    • MHC class I promoter binding protein antibody
    • NR2B2 antibody
    • nuclear receptor subfamily 2 group B member 2 antibody
    • RCoR 1 antibody
    • RCoR1 antibody
    • Retinoic acid receptor RXR beta antibody
    • RXR beta antibody
    • RXRB antibody
    • RXRbeta antibody
    see all

Anti-Retinoid X Receptor beta antibody - ChIP Grade images

  • Anti-Retinoid X Receptor beta antibody - ChIP Grade (ab5793) at 1/1000 dilution + Recombinant Human Retinoid X Receptor beta protein (ab82122) at 0.1 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Exposure time : 3 minutes

References for Anti-Retinoid X Receptor beta antibody - ChIP Grade (ab5793)

ab5793 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"