Anti-Retinoid X Receptor gamma antibody (ab24364)

Overview

  • Product nameAnti-Retinoid X Receptor gamma antibody
    See all Retinoid X Receptor gamma primary antibodies
  • Description
    Goat polyclonal to Retinoid X Receptor gamma
  • SpecificityThis does not cross-react with either RXR alpha or beta.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig, Deer
  • Immunogen

    Synthetic peptide:

    RQRSRERAES EAEC

    , corresponding to internal sequence amino acids 113-126 of Human Retinoid X Receptor gamma.

  • Positive control
    • Human Brain lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab24364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 51 kDa). Some bands of unknown identity were also consistently observed around 37 kDa. These bands were successfully blocked by incubation with the immunising peptide.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
    • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR2 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC109416 antibody
      • NR2B3 antibody
      • Nuclear receptor subfamily 2 group B member 3 antibody
      • OTTHUMP00000060418 antibody
      • Retanoic X receptor gamma antibody
      • Retinoic acid receptor RXR gamma antibody
      • Retinoic acid receptor RXR-gamma antibody
      • Retinoid X receptor gamma antibody
      • RXR G antibody
      • RXR gamma antibody
      • RXRC antibody
      • Rxrg antibody
      • RXRG_HUMAN antibody
      • RXRgamma antibody
      see all

    Anti-Retinoid X Receptor gamma antibody images

    • Anti-Retinoid X Receptor gamma antibody (ab24364) at 0.3 µg/ml + Human Brain lysate (in RIPA buffer). at 35 µg
      Developed using the ECL technique

      Predicted band size : 51 kDa
      Observed band size : 48 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 37 kDa,90 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 1 hour

    References for Anti-Retinoid X Receptor gamma antibody (ab24364)

    ab24364 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"