• Product nameAnti-RFC1 antibody
    See all RFC1 primary antibodies
  • Description
    Mouse monoclonal to RFC1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1-110 of Human RFC1


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG3
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab57860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThe elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA.
      Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.
    • Tissue specificityWide tissue distribution. Undetectable in placental tissue.
    • Sequence similaritiesBelongs to the activator 1 large subunit family.
      Contains 1 BRCT domain.
    • Post-translational
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • A1 140 kDa subunit antibody
      • A1 antibody
      • A1 P145 Activator 1 large subunit antibody
      • Activator 1 140 kDa subunit antibody
      • Activator 1 large subunit antibody
      • Activator 1 subunit 1 antibody
      • DNA binding Protein PO GA antibody
      • DNA-binding protein PO-GA antibody
      • MHC binding factor beta antibody
      • MHCBFB antibody
      • PO GA antibody
      • RECC1 antibody
      • Replication factor C (activator 1) 1, 145kDa antibody
      • Replication factor C 140 kDa subunit antibody
      • Replication factor C antibody
      • Replication factor C large subunit antibody
      • Replication factor C subunit 1 antibody
      • Replication factor C1 antibody
      • RF-C 140 kDa subunit antibody
      • RFC antibody
      • RFC1 antibody
      • RFC1_HUMAN antibody
      • RFC140 antibody
      • RFC140 Replication Factor C 140 kDa subunit antibody
      see all

    Anti-RFC1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57860 RFC1 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    References for Anti-RFC1 antibody (ab57860)

    ab57860 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57860.
    Please use the links above to contact us or submit feedback about this product.