Overview

  • Product name
  • Description
    Rabbit polyclonal to RFC3
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 80 and 110 of Human RFC3 (NP_002906.1)

  • Positive control
    • Human Breast Carcinoma and Colon Carcinoma

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab87314 was affinity purified using an epitope specific to RFC3 immobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab87314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
    • Sequence similarities
      Belongs to the activator 1 small subunits family.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • A1 38 kDa subunit antibody
      • Activator 1 38 kDa subunit antibody
      • Activator 1 subunit 3 antibody
      • HGNC:9971 antibody
      • MGC5276 antibody
      • Replication factor C (activator 1) 3 antibody
      • Replication factor C (activator 1) 3, 38kDa antibody
      • Replication factor C 3 antibody
      • Replication factor C 38 kDa subunit antibody
      • Replication factor C subunit 3 antibody
      • RF-C 38 kDa subunit antibody
      • RFC 38 kD subunit antibody
      • RFC 38 kDa subunit antibody
      • RFC3 antibody
      • RFC3_HUMAN antibody
      • RFC38 antibody
      see all

    Images

    • ab87314, at 1/250 dilution, staining RFC3 in formalin fixed, paraffin embedded Human colon carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

    References

    ab87314 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab87314.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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