Overview

  • Product name
  • Description
    Rabbit polyclonal to RGS1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-209 of Human RGS1 (UniProt Q08116).

  • Positive control
    • K562 cell lysate; Human Cal27 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab154973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 24 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.
  • Tissue specificity
    B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high.
  • Sequence similarities
    Contains 1 RGS domain.
  • Post-translational
    modifications
    Could be phosphorylated. Might be functionally regulated by protein kinase(s).
  • Information by UniProt
  • Database links
  • Alternative names
    • 1R20 antibody
    • B cell activation protein BL34 antibody
    • B-cell activation protein BL34 antibody
    • BL34 antibody
    • Early response protein 1R20 antibody
    • IER 1 antibody
    • IER1 antibody
    • Immediate early response 1 B cell specific antibody
    • immediate-early response 1, B-cell specific antibody
    • IR20 antibody
    • Regulator of G protein signalling 1 antibody
    • Regulator of G-protein signaling 1 antibody
    • RGS 1 antibody
    • RGS1 antibody
    • RGS1_HUMAN antibody
    see all

Images

  • Anti-RGS1 antibody (ab154973) at 1/1000 dilution + K562 whole cell lysate at 30 µg

    Predicted band size: 24 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human Cal27 xenograft tissue labeling RGS1 with ab154973 at 1/500 dilution.

References

ab154973 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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