Overview

  • Product name
  • Description
    Goat polyclonal to RGS1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    NLLNDLQANSLK

    , corresponding to C terminal amino acids 185-196 of Human RGS1.

  • Positive control
    • HepG2 lysate
  • General notes
    Principal Names – RGS1; regulator of G-protein signalling 1; 1R20; BL34; IER1; IR20; 1R20; Regulator of G-protein signaling 1 Official Gene Symbol - RGS1 GenBank Accession Number – NP_002913 LocusLink ID - 5996 (human); 50778 (mouse) Gene Ontology terms - GTPase activator; calmodulin binding; G-protein signaling, adenylate cyclase inhibiting pathway; immune response; signal transduction; plasma membrane

Properties

Applications

Our Abpromise guarantee covers the use of ab2715 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    Western Blot – Approx 25kDa band seen in HepG2 lysate.
    Recommended for use at 0.5-2.0µg/ml.
  • Target

    • Function
      Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.
    • Tissue specificity
      B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high.
    • Sequence similarities
      Contains 1 RGS domain.
    • Post-translational
      modifications
      Could be phosphorylated. Might be functionally regulated by protein kinase(s).
    • Information by UniProt
    • Database links
    • Alternative names
      • 1R20 antibody
      • B cell activation protein BL34 antibody
      • B-cell activation protein BL34 antibody
      • BL34 antibody
      • Early response protein 1R20 antibody
      • IER 1 antibody
      • IER1 antibody
      • Immediate early response 1 B cell specific antibody
      • immediate-early response 1, B-cell specific antibody
      • IR20 antibody
      • Regulator of G protein signalling 1 antibody
      • Regulator of G-protein signaling 1 antibody
      • RGS 1 antibody
      • RGS1 antibody
      • RGS1_HUMAN antibody
      see all

    References

    ab2715 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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