Overview

  • Product nameAnti-RGS22 antibody
    See all RGS22 primary antibodies
  • Description
    Rabbit polyclonal to RGS22
  • Tested applicationsSuitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: KDDVIEKGSK YMSESSKVIH LTSFTDISEC LKPQLDRRYA YTEEPRVKTV SDVGALGGSD MENLLQSLYV ENRAGFFFTK FCEHSGNKLW KNSVYFWFDL, corresponding to amino acids 601-700 of Human RGS22.

  • Positive control
    • Human kidney tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
  • Sequence similaritiesContains 2 RGS domains.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ40080 antibody
    • FLJ75004 antibody
    • MGC102908 antibody
    • PRTD-NY2 antibody
    • Regulator of G-protein signaling 22 antibody
    • RGS22 antibody
    • RGS22_HUMAN antibody
    see all

Anti-RGS22 antibody images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in cytoplasm. Recommended concentration of ab121739 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121739 at 1/125 dilution staining RGS22 in Paraffin-embedded Human Kidney tissue by Immunohistochemistry. Note: strong cytoplasmic positivity in tubular cells.

References for Anti-RGS22 antibody (ab121739)

ab121739 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"