Anti-RGS22 antibody - N-terminal (ab189942)

Overview

  • Product name
    Anti-RGS22 antibody - N-terminal
    See all RGS22 primary antibodies
  • Description
    Rabbit polyclonal to RGS22 - N-terminal
  • Host species
    Rabbit
  • Specificity
    At least four isoforms of RGS22 are known to exist; ab189942 will detect the three longest isoforms. ab189942 is predicted to not cross-react with other RGS proteins.
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human RGS22 (N terminal). The peptide corresponds to 19 amino acids.
    Database link: Q8NE09

  • Positive control
    • Human kidney and testis tissue. Jurkat cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab189942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 147 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
  • Sequence similarities
    Contains 2 RGS domains.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ40080 antibody
    • FLJ75004 antibody
    • MGC102908 antibody
    • PRTD-NY2 antibody
    • Regulator of G-protein signaling 22 antibody
    • RGS22 antibody
    • RGS22_HUMAN antibody
    see all

Images

  • Immunohistochemistry of formalin-fixed, paraffin-embedded Human kidney tissue labeling RGS22 with ab189942 at 5 µg/ml.

  • Lane 1 : Anti-RGS22 antibody - N-terminal (ab189942) at 1 µg/ml
    Lane 2 : Anti-RGS22 antibody - N-terminal (ab189942) at 2 µg/ml

    All lanes : Jurkat cell lysate

    Predicted band size: 147 kDa

  • Immunofluorescence analysis of Human testis tissue labeling RGS22 using ab189942 at 20 µg/ml.

References

ab189942 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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