ab94242 is a 293T cell transfected lysate in which Human RGS3 has been transiently over-expressed using a pCMV-RGS3 Full length plasmid. The lysate is provided in 1X Sample Buffer. Note: For more detailes about how the transfected lysate was prepared view preparation notes
Function: Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
Similarity: Contains 1 C2 domain.
Contains 1 PDZ (DHR) domain.
Contains 1 RGS domain.
PTM: Phosphorylated by cyclic GMP-dependent protein kinase.