Overview

  • Product name
  • Description
    Rabbit polyclonal to RGS6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Chicken
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 209-449 of RGS6 (UniProt ID: P49758).

  • Positive control
    • PC3 whole cell lysate; Human H1299 xenograft tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab155809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 54 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/Gbeta5 dimer.
  • Sequence similarities
    Contains 1 DEP domain.
    Contains 1 G protein gamma domain.
    Contains 1 RGS domain.
  • Cellular localization
    Cytoplasm. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ43552 antibody
    • G protein signaling 6 regulator antibody
    • GAP antibody
    • GTPase activating protein antibody
    • MGC142132 antibody
    • Regulator of G protein signaling 6 antibody
    • Regulator of G protein signalling 6 antibody
    • Regulator of G-protein signaling 6 antibody
    • RGS 6 antibody
    • RGS6 antibody
    • RGS6_HUMAN antibody
    • S914 antibody
    see all

Images

  • Anti-RGS6 antibody (ab155809) at 1/1000 dilution + PC3 whole cell lysate at 30 µg

    Predicted band size: 54 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Human H1299 xenograft tissue, labeling RGS6 using ab155809 at 1/500 dilution.

References

This product has been referenced in:
  • Jiang N  et al. Decreased RGS6 expression is associated with poor prognosis in pancreatic cancer patients. Int J Clin Exp Pathol 7:4120-7 (2014). IHC ; Human . Read more (PubMed: 25120791) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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