Overview

  • Product name
    Anti-RGS7 antibody - C-terminal
    See all RGS7 primary antibodies
  • Description
    Rabbit polyclonal to RGS7 - C-terminal
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human RGS7 aa 447-477 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P49802

  • Positive control
    • K562 cell line lysates. Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab170801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 58 kDa.

Target

  • Relevance
    RGS7 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP bound form. Activity on G(o) alpha is specifically enhanced by the RGS6/GNG5 dimer. RGS7 may play a role in synaptic vesicle exocytosis and may play an important role in the rapid regulation of neuronal excitability and the cellular responses to short lived stimulations.
  • Cellular localization
    Cytoplasmic
  • Database links
  • Alternative names
    • OTTHUMP00000037994 antibody
    • Regulator of G protein signalling 7 antibody
    • Regulator of G-protein signaling 7 antibody
    • Regulator of G-protein signaling RGS7 antibody
    • Regulator of G-protein signalling 7 antibody
    see all

Images

  • Immunohistochemical analysis of Formalin/PFA-fixed paraffin-embedded Human brain tissue labeling RGS7 with ab170801 at a 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-RGS7 antibody - C-terminal (ab170801) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 58 kDa

References

ab170801 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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